BCL11A 抗体 (AA 1-89)
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Quick Overview for BCL11A 抗体 (AA 1-89) (ABIN782364)
抗原
See all BCL11A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-89
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特异性
- Recognizes Bcl-11A
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Protein A Chromatography
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免疫原
- BCL11A (NP_060484, 1 a.a. ~ 89 a.a) partial recombinant protein with GST tag.
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS, pH 7.2
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze-thaw cycles.
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- BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))
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别名
- Bcl-11A
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背景
- This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.Synonyms: B-cell CLL/lymphoma 11A, B-cell lymphoma/leukemia 11A, BCL11A, COUP-TF-interacting protein 1, CTIP1, EVI9, Ecotropic viral integration site 9 protein homolog, KIAA1809
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基因ID
- 53335
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NCBI登录号
- NP_060484
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UniProt
- Q9H165
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途径
- Regulation of Cell Size
抗原
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