LI Cadherin 抗体 (AA 24-132)
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北京 101111
Quick Overview for LI Cadherin 抗体 (AA 24-132) (ABIN782351)
抗原
See all LI Cadherin 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 24-132
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特异性
- Recognizes Cadherin-17
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Protein A Chromatography
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免疫原
- CDH17 antibody was raised against CDH17 (NP_004054, 24 a.a. ~ 132 a.a) partial recombinant protein with GST tag.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS, pH 7.2
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注意事项
- Avoid freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C or -80 °C.
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- LI Cadherin
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别名
- Cadherin-17
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背景
- The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin beta, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.Synonyms: CDH17, HPT-1, HPT1, Intestinal peptide-associated transporter HPT-1, Liver-intestine cadherin
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基因ID
- 1015
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NCBI登录号
- NP_001138135
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UniProt
- Q12864
抗原
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