Optimal working dilution should be determined by the investigator.
限制
仅限研究用
缓冲液
PBS, pH 7.2
注意事项
Avoid freeze-thaw cycles.
储存条件
-20 °C
储存方法
Store the antibody (in aliquots) at -20 °C or -80 °C.
抗原
LI Cadherin
别名
Cadherin-17
背景
The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin beta, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.Synonyms: CDH17, HPT-1, HPT1, Intestinal peptide-associated transporter HPT-1, Liver-intestine cadherin