RND3
适用: 人, 大鼠
ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
浓度
1.0 mg/mL
缓冲液
PBS, pH 7.2
注意事项
Avoid freeze-thaw cycles.
储存条件
-20 °C
储存方法
Store the antibody (in aliquots) at -20 °C or -80 °C.
抗原
RND3
(rho Family GTPase 3 (RND3))
别名
RND3 / ARHE
背景
Rho-related GTP-binding protein RhoE, also known as RND3, is a small GTPase of the Ras superfamily that regulate the organization of the actin cytoskeleton in response to extracellular growth factors. RND3 activity leads to a decrease in stress fibers and increased cell migration, at least in part through regulation of the Rho-dependent kinase ROCK1. Also, RND3 has been implicated in inhibition of DNA-damage induced apoptosis and cell cycle arrest.Synonyms: MemB protein, RHO8, RHOE, Rho family GTPase 3, Rho-related GTP-binding protein RhoE