RND3 抗体 (AA 1-245)
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Quick Overview for RND3 抗体 (AA 1-245) (ABIN782334)
抗原
See all RND3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-245
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特异性
- Recognizes RND3 / ARHE.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Protein A Chromatography
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免疫原
- RND3 antibody was raised against RND3 (AAH12513, 1 a.a. ~ 245 a.a) full-length recombinant protein with GST tag.
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.2
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注意事项
- Avoid freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C or -80 °C.
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- RND3 (rho Family GTPase 3 (RND3))
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别名
- RND3 / ARHE
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背景
- Rho-related GTP-binding protein RhoE, also known as RND3, is a small GTPase of the Ras superfamily that regulate the organization of the actin cytoskeleton in response to extracellular growth factors. RND3 activity leads to a decrease in stress fibers and increased cell migration, at least in part through regulation of the Rho-dependent kinase ROCK1. Also, RND3 has been implicated in inhibition of DNA-damage induced apoptosis and cell cycle arrest.Synonyms: MemB protein, RHO8, RHOE, Rho family GTPase 3, Rho-related GTP-binding protein RhoE
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基因ID
- 390
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NCBI登录号
- NP_005159
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UniProt
- P61587
抗原
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