EBI3 抗体
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Quick Overview for EBI3 抗体 (ABIN781990)
抗原
See all EBI3 (IL-27b) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The monoclonal antibody DNT27 reacts with Mouse Epstein-Barr Virus-induced gene 3 (EBI3).
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交叉反应 （详细）
- Species reactivity (tested):Human and Mouse.
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纯化方法
- Affinity Chromatography
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亚型
- IgG2a
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anti-Interleukin-27 subunit beta (IL-27b) (AA 21-229) antibody
IL-27b 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 2-3# unconjugated
anti-Interleukin-27 subunit beta (IL-27b) antibodyIL-27b 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Interleukin-27 subunit beta (IL-27b) antibodyIL-27b 适用: 小鼠 ELISA, IP, Neut 宿主: 小鼠 Monoclonal V1-4C4-22 unconjugated
anti-Interleukin-27 subunit beta (IL-27b) (AA 21-227) antibodyIL-27b 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-27 subunit beta (IL-27b) (AA 153-181), (C-Term) antibodyIL-27b 适用: 人 WB 宿主: 兔 Polyclonal RB30602 unconjugated
anti-Interleukin-27 subunit beta (IL-27b) (AA 21-229) antibodyIL-27b 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-27 subunit beta (IL-27b) (AA 129-229) antibodyIL-27b 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin-27 subunit beta (IL-27b) (C-Term) antibodyIL-27b 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-27 subunit beta (IL-27b) (AA 21-229) antibodyIL-27b 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 1-1# unconjugated
anti-Interleukin-27 subunit beta (IL-27b) (AA 129-229) antibodyIL-27b 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1D3 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffer containing 0.09 % Sodium Azide and stabilizer if necessary
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))
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别名
- EBI3 / IL27B
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背景
- EBI3 is a 229 amino acid cytokine belonging to the type I cytokine receptor family (type 3 subfamily) with a signal peptide, 2 potential N-linked glycosylation sites, an LSDWS motif, 2 fibronectin type-III domains. It is usually induced due to infection of B lymphocytes by Epstein-Barr virus and due to expression of an EBV encoded latent membrane protein. EBI3 is a subunit of two heterodimeric cytokines interleukin-27 (IL27) and IL35. It is a secreted glycoprotein associated with calnexin and is a heterodimer with an alpha and a beta subunit. It is also known to interact with SQSTM1 and is responsible for the rapid clonal expansion of naive but not memory CD4 (+) T-cells. It strongly synergizes with IL-12 and trigger IFN-gamma production of naive CD4 (+) T-cells. It mediates its biologic effects through the cytokine receptor WSX-1/TCCR. It triggers signaling in T cells, B cells, and myeloid cells and along with p35 it acts as an important immunomodulator. It is usually expressed in various hemopoietic tissues and cell lines.Synonyms: EBV-induced gene 3 protein, Epstein-Barr virus-induced gene 3 protein, IL-27 subunit beta, IL-27B, Interleukin-27 subunit beta
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基因ID
- 50498
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NCBI登录号
- NP_056581
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UniProt
- O35228
抗原
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