LY75/DEC-205 抗体
Quick Overview for LY75/DEC-205 抗体 (ABIN781804)
抗原
See all LY75/DEC-205 (LY75) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes CD205, an approx. 200 kDa C-type lectin transmembrane protein of the MMR (macrophage mannose receptor) family, expressed at high levels on dendritic cells and thymic epithelial cells, and at low levels on lymphocytes, NK cells and monocytes.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Protein-A affinity chromatography
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纯度
- > 95 % pure (by SDS-PAGE)
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免疫原
- Recombinant Fc-tagged human CD205
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亚型
- IgG1
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anti-Lymphocyte Antigen 75 (LY75) antibody (PE)
LY75 适用: 人 FACS 宿主: 小鼠 Monoclonal HD30 PE
anti-Lymphocyte Antigen 75 (LY75) antibodyLY75 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4B10E11 unconjugated
anti-Lymphocyte Antigen 75 (LY75) (AA 440-680) antibodyLY75 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Antigen 75 (LY75) antibodyLY75 适用: 人 WB, FACS, IHC (fro) 宿主: 小鼠 Monoclonal HD30 unconjugated
anti-Lymphocyte Antigen 75 (LY75) (AA 1520-1666) antibodyLY75 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3A4A10 unconjugated
anti-Lymphocyte Antigen 75 (LY75) (C-Term) antibodyLY75 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Antigen 75 (LY75) (Internal Region) antibodyLY75 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Antigen 75 (LY75) antibody (PE)LY75 适用: Cow, 绵羊 FACS 宿主: 小鼠 Monoclonal IL-A114 PE
anti-Lymphocyte Antigen 75 (LY75) antibody (APC)LY75 适用: 人 FACS 宿主: 小鼠 Monoclonal HD30 APC
anti-Lymphocyte Antigen 75 (LY75) (AA 646-675) antibodyLY75 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23558 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))
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别名
- CD205 / DEC-205
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背景
- CD205, also known as DEC-205, is an endocytic receptor of macrophage mannose receptor family. This 205 kDa C-type lectin transmembrane protein mediates adsorptive uptake and its intracellular domain contains coated pit localization sequence and distal acidic motif, which is required for recycling beyond early endosomes through deeper MHC II+ late endosomes and lysosomes. This unique pathway of receptor-mediated uptake proves to be necessary for presentation of antigenic peptides at low doses of ligand. CD205 is responsible for uptake and processing of captured antigens for dendritic cells.Synonyms: C-type lectin domain family 13 member B, CLEC13B, DEC205, LY75, Lymphocyte antigen 75, gp200-MR6
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基因ID
- 100526664
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NCBI登录号
- NP_001185688
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UniProt
- O60449
抗原
-
