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- 抗原
- STRO-1
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF)
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- Precipitation Methods and Ion Exchange Chromatography
- 免疫原
- Human CD34 positive bone marrow cells.
- 克隆位点
- STRO-1
- 亚型
- IgM
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anti-STRO-1 antibody
适用: 人, 兔, 大鼠 FACS, ICC 宿主: 小鼠 Monoclonal STRO-1 unconjugated
anti-STRO-1 antibody (APC)适用: 人, 兔, 大鼠 FACS 宿主: 小鼠 Monoclonal STRO-1 APC
anti-STRO-1 antibody (PE)适用: 人, 兔, 大鼠 FACS 宿主: 小鼠 Monoclonal STRO-1 PE
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Tris buffered saline (TBS), pH ~8.0, 15 mM Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- STRO-1
- 背景
- STRO-1 is a cell surface antigen expressed by stromal elements in human bone marrow, identified by monoclonal antibody STRO-1. Approximately 10 % of mononuclear cells, greater than 95 % of which are nucleated erythroid precursors, are STRO-1 positive, whereas the CFU-GM (colony-forming unit granulocyte-macrophage), BFU-E (erythroid burst) and CFU-Mix (mixed colonies) committed progenitor cells are negative. CFU-F (fibroblast colony-forming cells) are present exclusively in the STRO-1 positive population. When plated under long-term bone marrow culture conditions, STRO-1 positive cells generate adherent cell layers containing multiple stromal cell types, including adipocytes, smooth muscle cells, osteoblasts, chondrocytes, and fibroblastic elements. In combination with glycophorin A, STRO-1 is a useful marker for identification of mesenchymal stem cells. STRO-1 and CD117 are markers for osteosarcoma cells.
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