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STRO-1 抗体

This anti- antibody is a 小鼠 单克隆 antibody detecting in FACS 和 IF. Suitable for 人.
产品编号 ABIN781729
发货至: 中国

Quick Overview for STRO-1 抗体 (ABIN781729)

抗原

STRO-1

适用

  • 7
  • 3
  • 3

宿主

  • 7
小鼠

克隆类型

  • 4
  • 3
单克隆

标记

  • 3
  • 3
  • 1
非结合性

应用范围

  • 7
  • 3
  • 2
Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

STRO-1
  • 交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Precipitation Methods and Ion Exchange Chromatography

    免疫原

    Human CD34 positive bone marrow cells.

    亚型

    IgM
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Tris buffered saline (TBS), pH ~8.0, 15 mM Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    STRO-1

    背景

    STRO-1 is a cell surface antigen expressed by stromal elements in human bone marrow, identified by monoclonal antibody STRO-1. Approximately 10 % of mononuclear cells, greater than 95 % of which are nucleated erythroid precursors, are STRO-1 positive, whereas the CFU-GM (colony-forming unit granulocyte-macrophage), BFU-E (erythroid burst) and CFU-Mix (mixed colonies) committed progenitor cells are negative. CFU-F (fibroblast colony-forming cells) are present exclusively in the STRO-1 positive population. When plated under long-term bone marrow culture conditions, STRO-1 positive cells generate adherent cell layers containing multiple stromal cell types, including adipocytes, smooth muscle cells, osteoblasts, chondrocytes, and fibroblastic elements. In combination with glycophorin A, STRO-1 is a useful marker for identification of mesenchymal stem cells. STRO-1 and CD117 are markers for osteosarcoma cells.
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