CD16 抗体
Quick Overview for CD16 抗体 (ABIN781725)
抗原
See all CD16 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody recognizes CD16, the low affinity receptor for IgG (FcγRIII). It detects both isoforms.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Affinity chromatography
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亚型
- IgG1
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anti-CD16 (CD16) antibody
CD16 适用: 人, Non-Human Primate FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal 3G8 unconjugated
anti-CD16 (CD16) antibodyCD16 适用: 人, Non-Human Primate FACS, IP 宿主: 小鼠 Monoclonal LNK16 unconjugated
anti-CD16 (CD16) antibody (FITC)CD16 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal LNK16 FITC
anti-CD16 (CD16) antibodyCD16 适用: 人, Pig, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-168 unconjugated
anti-CD16 (CD16) antibodyCD16 适用: 人 FACS, IP, WB 宿主: 小鼠 Monoclonal MEM-154 unconjugated
anti-CD16 (CD16) antibodyCD16 适用: 人 FACS, IP, WB, Func 宿主: 小鼠 Monoclonal MEM-154 unconjugated
anti-CD16 (CD16) antibody (Biotin)CD16 适用: 人 FACS, IP, WB 宿主: 小鼠 Monoclonal MEM-154 Biotin
anti-CD16 (CD16) (AA 17-208) antibodyCD16 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2G10A9 unconjugated
anti-CD16 (CD16) antibodyCD16 适用: 人, Non-Human Primate FACS, IP, Func, IHC (fro) 宿主: 小鼠 Monoclonal 3G8 unconjugated
anti-CD16 (CD16) antibodyCD16 适用: 人, Pig, 绵羊, Cow, 马 FACS, Func 宿主: 小鼠 Monoclonal KD1 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Reconstitute by adding 0.5 mL distilled water.
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缓冲液
- Stock solution contains 0.4 mg/mL IgG, phosphate buffered saline pH 7.2 (PBS), 5 mg/mL bovine serum albumin (BSA), and 0.09 % sodium azide as a preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Lyophilized product can be stored at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.
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- CD16
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别名
- CD16
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背景
- CD16 is expressed on the majority of NK cells, on granulocytes, monocytes and macrophages, and on a subset of T cells. CD16 is involved in antibody-dependent cellular cytotoxicity (ADCC). This molecule is encoded by FcγRIII-A or FcγRIII-B genes. The genetic heterogeneity of FcγRIII generates alternative membrane-anchored proteins with distinct signalling capacities when cross-linked by immune complexes. CD16 exists in two distinct forms, as a single-pass type I integral membrane protein (CD16a), and as a glycosyl phosphatidyl inositol (GPI) form (CD16b). In humans, the transmembrane form is expressed on NK cells and macrophages while the GPI linked form is expressed on granulocytes.Synonyms: CD16A, FCG3, FCGR3, FCGR3A, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, FcR-10, FcRIII, FcRIIIa, IGFR3, IgG Fc receptor III-2, Low affinity immunoglobulin gamma Fc region receptor III-A
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基因ID
- 2214
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NCBI登录号
- NP_000560
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UniProt
- P08637
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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