Ferritin 抗体
Quick Overview for Ferritin 抗体 (ABIN781724)
抗原
See all Ferritin (FE) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Affinity chromatography
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免疫原
- Ferritin from human spleen and liver
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Reconstitute by adding 0.5 mL distilled water.
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缓冲液
- Stock solution contains 0.4 mg/mL IgG, phosphate buffered saline pH 7.2 (PBS), 10 mg/mL bovine serum albumin (BSA) as a stabilizer and 0.01 % thimerosal as a preservative
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.
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- Ferritin (FE)
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别名
- Ferritin
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背景
- Ferritin consists of a mineral core of hydrated ferric oxide, and a multi-subunit protein shell which englobes the former and assures its solubility in an aqueous environment. It is mainly localized intracellularly in cells of the reticuloendothelial system as well as in liver, spleen and bone marrow. Elevated serum levels are found in patients with iron overload and in other diseases such as pernicious anaemia, chronic inflammations such as rheumatoid arthritis (RA), hepatocellular carcinoma and Hodgkin's disease. Ferritin consists of two components, the apoferritin and the iron core (FeIII - hydroxyphosphate-micelle). The apoferritin is a globular protein built up of 24 subunits that can bind up to 4500 iron atoms. Other non-ferrous metal ions such as Al or Be can also bind to ferritin, which acts partly as a metal ion detoxicant.Synonyms: FTH, FTL, Ferritin H subunit, Ferritin L subunit
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途径
- Transition Metal Ion Homeostasis
抗原
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