Selectin E/CD62e 抗体 (FITC)
Quick Overview for Selectin E/CD62e 抗体 (FITC) (ABIN781710)
抗原
See all Selectin E/CD62e (SELE) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody detects CD62E / E-Selectin.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Affinity chromatography
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免疫原
- LPS-stimulated human endothelial cells
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亚型
- IgG2a
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anti-Selectin E (SELE) (AA 501-612) antibody
SELE 适用: 人, Pig, 小鼠, 大鼠 WB, ELISA, FACS, IHC (fro), IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Selectin E (SELE) (AA 22-230) antibodySELE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Selectin E (SELE) (N-Term) antibodySELE 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Selectin E (SELE) (AA 108-238) antibodySELE 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Selectin E (SELE) (AA 260-420) antibodySELE 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Selectin E (SELE) antibodySELE 适用: 小鼠 WB, IHC, ELISA, IP, FACS, ICC, IHC (fro), Func 宿主: 大鼠 Monoclonal UZ5 unconjugated
anti-Selectin E (SELE) antibodySELE 适用: 人 ELISA 宿主: 小鼠 Monoclonal B-P7 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate buffered saline pH 7.2 (PBS), 10 mg/mL bovine serum albumin (BSA) as a stabilizer and 0.09 % sodium azide as a preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- Selectin E/CD62e (SELE) (Selectin E (SELE))
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别名
- CD62E / E-Selectin
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背景
- CD62E belongs to the selectin family and is thought to mediate rolling of myeloid cells and a subset of memory T cells on activated endothelium. The antigen is a 589 amino acid transmembrane protein. It consists of a C-type lectin-like domain, an epidermal growth factor (EGF)-like domain, six short consensus repeat (SCR) domains, a transmembrane domain and a cytoplasmic tail. CD62E is a counter-receptor for sialyl Lewis X, sialyl Lewis a and CLA (cutaneous lymphocyte antigen). It is involved in adhesion between myeloid cells and activated endothelium, and supports leucocytes rolling. Some skin-associated memory T cells express CLA, and it may be that CD62E is also involved in their homing to cutaneous sites of chronic inflammation. In addition, CD62E may also be involved in tumour metastasis. A soluble form of CD62E has been reported to mediate angiogenesis in pathological disorders.Synonyms: CD62 antigen-like family member E, ELAM1, Endothelial leukocyte adhesion molecule 1, LECAM2, Leukocyte-endothelial cell adhesion molecule 2, SELE
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基因ID
- 6401
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NCBI登录号
- NP_000441
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UniProt
- P16581
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途径
- Thromboxane A2 Receptor Signaling
抗原
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