TPMT 抗体
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北京 101111
Quick Overview for TPMT 抗体 (ABIN781549)
抗原
See all TPMT 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody recognizes human TPMT. Other species not tested.
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纯化方法
- Protein-G affinity chromatography
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- TPMT (Thiopurine S-Methyltransferase (TPMT))
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别名
- Thiopurine Methyltransferase (TPMT)
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背景
- TPMT (Thiopurine S-methyltransferase) is a very important enzyme for the metabolizm of thiopurine compounds. TPMT pharmacogenetics has been studied extensively because of its clinical significance. Many patients got benefited from the knowledge of TPMT genotype-phenotype correlation. Also, TPMT activity exhibits autosomal codominant genetic polymorphism, and patients inheriting TPMT-deficiency are at high risk of potentially fatal hematopoietic toxicity.Synonyms: Thiopurine S-methyltransferase
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基因ID
- 7172
抗原
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