CD32/CD16 抗体 (Biotin)
-
- 抗原 See all CD32/CD16 products
- CD32/CD16
- 适用
- 小鼠
-
宿主
- 大鼠
-
克隆类型
- 单克隆
-
标记
- This CD32/CD16 antibody is conjugated to Biotin
-
应用范围
- Flow Cytometry (FACS)
- 产品特性
- Synonyms: IgG Fc receptor III-2, Fc-gamma RIII-alpha, Fc-gamma RIIIa, FcRIIIa, Fc-gamma RIII, FcRIII,CD16a, FcR mouse Seroblock, FCGR3A, FCG3, IGFR3, Fc gamma receptor IIB, Fc-gamma-RIIB,FcRII, Ly-17, Fcgr2, Low affinity immunoglobulin gamma Fc region receptor III-A, Low affinityimmunoglobulin gamma Fc region receptor III-B
- 克隆位点
- KT1632
- 亚型
- IgG2a
-
-
- 应用备注
-
Flow cytometry (1 g is the maximum amount of reagent required per 10^6 cells). Tissue Distribution by Flow Cytometry Analysis: Mouse Strain: BALB/cCell Concentration: 1x10^6 cells per testsAntibody Concentration Used: 0.1 g/10^6 cellsIsotypic Control: FITC Rat IgG2a.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
-
Store the antibody at 2 - 8 °C for up to one month ore (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
-
- 抗原
- CD32/CD16
- 别名
- CD16/CD32 (CD32/CD16 产品)
- 背景
- The lymphocyte Fc-gamma Receptors recognize the Fc portion of IgG, presented either as immune complexes or as free antibody. The different classes of receptors are distinct because of varying size, tissue distribution and affinity for IgGs. The Fc type II receptor is expressed on a wide variety of cells including B cells, hematopoietic cells, monocyte/macrophages, neutrophils, platelets, Langerhans cells, eosinophils, basophils, trophoblasts, and endothelial cells of the placenta. The Fc-gamma type III receptors are higher affinity than the type II and are expressed on macrophages, NK cells and neutrophils. Both types of receptors can be expressed on the same cell and in varying ratios. The receptors are constitutively expressed, although cytokines and lymphokines can modulate their expression. Besides identifying Fc-gammaR+ cells, monoclonal antibodies to the Fc-gammaII/III receptor have been used to block Fc receptor binding of IgG, Fcmediated signal transduction and effector functions, clearance of immune complexes and to attenuate infection by organisms dependent on Fc-gamma R for parasitic invasion.Synonyms: CD16a, FCG3, FCGR3A, Fc gamma receptor IIB, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, Fc-gamma-RIIB, FcR mouse Seroblock, FcRII, FcRIII, FcRIIIa, Fcgr2, IGFR3, IgG Fc receptor III-2, Low affinity immunoglobulin gamma Fc region receptor III-A, Low affinity immunoglobulin gamma Fc region receptor III-B, Ly-17
-