SMAD1 抗体
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北京 101111
Quick Overview for SMAD1 抗体 (ABIN781341)
抗原
See all SMAD1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Cytoplasm
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纯化方法
- Protein G-Sepharose affinity purified.
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免疫原
- Recombinant fragment of human SMAD1 (C-terminus).
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亚型
- IgG
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应用备注
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 50µg/50µl
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缓冲液
- 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))
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别名
- SMAD1
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背景
- SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation.
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分子量
- 40kDa
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NCBI登录号
- NM_001003688
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途径
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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