Leptin Receptor 抗体
Quick Overview for Leptin Receptor 抗体 (ABIN781204)
抗原
See all Leptin Receptor (LEPR) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Plasma membrane
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纯化方法
- Protein G-Sepharose affinity purified.
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免疫原
- Recombinant fragment of Human LEPR (N-terminus).
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亚型
- IgG
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应用备注
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 50µg/50µl
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缓冲液
- 0.02% Sodium Azide and 50% glycerol, 1% BSA ,PBS, pH7.4.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- Leptin Receptor (LEPR)
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别名
- LEPR
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背景
- Leptin receptor (LEPR, OB-R) is a type I cytokine receptor family protein with significant amino acid sequence identity with gp130, G-CSF receptor, and LIF receptor. The transcript was reported to be expressed predominantly in regions of the hypothalamus previously thought to be important in body weight regulation. OB-R binds leptin with high affinity and is a potent leptin antagonist.
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分子量
- 120kDa
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NCBI登录号
- NM_002303
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途径
- JAK/STAT Signaling, AMPK Signaling, Feeding Behaviour
抗原
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