CD83 抗体
Quick Overview for CD83 抗体 (ABIN775709)
抗原
See all CD83 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD83 Purified
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特异性
- The mouse monoclonal antibody HB15e recognizes an extracellular epitope of CD83, a 40-45 kDa type I glycoprotein expressed on mature dendritic cells.
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交叉反应 （详细）
- Human, Non-Human Primates
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Human CD83-transfected Cos cells
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亚型
- IgG1 kappa
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anti-CD83 (CD83) (AA 1-205) antibody
CD83 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3G10-1F4 unconjugated
anti-CD83 (CD83) antibodyCD83 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-CD83 (CD83) (AA 20-144) antibodyCD83 适用: 人 ELISA 宿主: 小鼠 Monoclonal 8A4C11 unconjugated
anti-CD83 (CD83) (AA 32-100) antibodyCD83 适用: 人, 小鼠 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD83 (CD83) (AA 24-205) antibodyCD83 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD83 (CD83) antibodyCD83 适用: 人, Baboon, Chimpanzee, Cynomolgus, 猕猴, Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius) FACS, IP, IF, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal HB15e unconjugated
anti-CD83 (CD83) (AA 1-205) antibodyCD83 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-CD83 (CD83) (Internal Region) antibodyCD83 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD83 (CD83) antibodyGMP Grade CD83 适用: 人 FACS 宿主: 小鼠 Monoclonal HB15e unconjugated
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应用备注
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Flow cytometry:Recommended dilution: 1-4 μg/mL, Positive control: peripheral blood-derived dendritic cells.
Immunohistochemistry (frozen sections): acetone fixation. -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- CD83
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别名
- CD83
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背景
- CD83 Molecule,CD83 is a 40-45 kDa heavily glycosylated type I cell surface glycoprotein of immunoglobulin family. It is expressed on the surface of mature dendritic cells, Langerhans cells in the skin, and interdigitating reticulum cells in the lymphoid tissues. Low expression of CD83 has been reported in activated T and B cells. Cytoplasmic expression of CD83 can be detected also in monocytes and macrophages. CD83 is involved in modulation of antigen presentation. Soluble CD83 has immunoregulatory functions, it is able to down-regulate dendritic cell maturation and stimulation of T cells. In the developing immune system, release of soluble CD83 from dendritic cells upon stimulation by gram-positive or gram-negative bacteria has anti-allergic effect. Herpes simplex virus, on the other hand, causes CD83 degradation in mature dendritic cells.,BL11, HB15
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基因ID
- 9308
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UniProt
- Q01151
抗原
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