LY75/DEC-205 抗体
(1 reference)Quick Overview for LY75/DEC-205 抗体 (ABIN775707)
抗原
See all LY75/DEC-205 (LY75) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD205 Purified
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特异性
- The mouse monoclonal antibody HD30 recognizes an extracellular epitope of CD205, an approx. 200 kDa C-type lectin transmembrane protein of the MMR (macrophage mannose receptor) family, expressed at high levels on dendritic cells and thymic epithelial cells, and at low levels on lymphocytes, NK cells and monocytes.
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交叉反应 （详细）
- Human
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Recombinant Fc-tagged human CD205
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亚型
- IgG1 kappa
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anti-Lymphocyte Antigen 75 (LY75) antibody (PE)
LY75 适用: 人 FACS 宿主: 小鼠 Monoclonal HD30 PE
anti-Lymphocyte Antigen 75 (LY75) antibodyLY75 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4B10E11 unconjugated
anti-Lymphocyte Antigen 75 (LY75) (AA 440-680) antibodyLY75 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Antigen 75 (LY75) (AA 1520-1666) antibodyLY75 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3A4A10 unconjugated
anti-Lymphocyte Antigen 75 (LY75) (C-Term) antibodyLY75 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Antigen 75 (LY75) (Internal Region) antibodyLY75 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Antigen 75 (LY75) antibody (PE)LY75 适用: Cow, 绵羊 FACS 宿主: 小鼠 Monoclonal IL-A114 PE
anti-Lymphocyte Antigen 75 (LY75) antibody (APC)LY75 适用: 人 FACS 宿主: 小鼠 Monoclonal HD30 APC
anti-Lymphocyte Antigen 75 (LY75) (AA 646-675) antibodyLY75 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23558 unconjugated
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应用备注
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Western blotting: Only non-denatured samples.
Flow cytometry: Recommended dilution: 1-4 μg/mL -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "Generation of anti-human DEC205/CD205 monoclonal antibodies that recognize epitopes conserved in different mammals." in: Journal of immunological methods, Vol. 377, Issue 1-2, pp. 15-22, (2012) (PubMed).
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: "Generation of anti-human DEC205/CD205 monoclonal antibodies that recognize epitopes conserved in different mammals." in: Journal of immunological methods, Vol. 377, Issue 1-2, pp. 15-22, (2012) (PubMed).
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- LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))
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别名
- CD205
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背景
- Lymphocyte antigen 75,CD205, also known as DEC-205, is an endocytic receptor of macrophage mannose receptor family. This 205 kDa C-type lectin transmembrane protein mediates adsorptive uptake and its intracellular domain contains coated pit localization sequence and distal acidic motif, which is required for recycling beyond early endosomes through deeper MHC II+ late endosomes and lysosomes. This unique pathway of receptor-mediated uptake proves to be necessary for presentation of antigenic peptides at low doses of ligand. CD205 is responsible for uptake and processing of captured antigens for dendritic cells.,DEC-205, LY75, CLEC13B
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基因ID
- 4065
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UniProt
- O60449
抗原
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