RAB5 抗体 (AA 8-100)
Quick Overview for RAB5 抗体 (AA 8-100) (ABIN763526)
抗原
See all RAB5 (RAB5A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 8-100
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human RAB5.
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亚型
- IgG
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anti-RAB5A, Member RAS Oncogene Family (RAB5A) (C-Term) antibody
RAB5A 适用: 人, 小鼠, 大鼠, Cow, 猴, 犬, 绵羊, 马, 兔, 豚鼠, Pig, Hamster, 小鸡, Avian, Cat, 驴, 山羊 WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-RAB5A, Member RAS Oncogene Family (RAB5A) (C-Term) antibodyRAB5A 适用: 人, 小鼠, 大鼠, Cow, 猴, 犬, 绵羊, 马, 兔, 豚鼠, Pig, Hamster, 小鸡, Avian, Cat, 驴, 山羊 WB, IF 宿主: 山羊 Polyclonal unconjugated
anti-RAB5A, Member RAS Oncogene Family (RAB5A) antibodyRAB5A 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAB5A, Member RAS Oncogene Family (RAB5A) (AA 1-215) antibodyRAB5A 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 3H5C11 unconjugated
anti-RAB5A, Member RAS Oncogene Family (RAB5A) (AA 1-215) antibodyRAB5A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAB5A, Member RAS Oncogene Family (RAB5A) antibody (Atto 390)RAB5A 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 390
anti-RAB5A, Member RAS Oncogene Family (RAB5A) (AA 182-211) antibodyRAB5A 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-RAB5A, Member RAS Oncogene Family (RAB5A) antibody (HRP)RAB5A 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal HRP
anti-RAB5A, Member RAS Oncogene Family (RAB5A) antibody (FITC)RAB5A 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal FITC
anti-RAB5A, Member RAS Oncogene Family (RAB5A) antibody (Biotin)RAB5A 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Biotin
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))
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别名
- Rab5
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背景
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Synonyms: RAB 5, RAB 5A, RAB5A, RAB5A member RAS oncogene family, RAB5A_HUMAN, RAS associated protein RAB5A, Ras related protein Rab 5A, Ras-related protein Rab-5A.
Background: Rab5-related subfamily. This subfamily includes Rab5 and Rab22 of mammals, Ypt51/Ypt52/Ypt53 of yeast, and RabF of plants. The members of this subfamily are involved in endocytosis and endocytic-sorting pathways. In mammals, Rab5 GTPases localize to early endosomes and regulate fusion of clathrin-coated vesicles to early endosomes and fusion between early endosomes. In yeast, Ypt51p family members similarly regulate membrane trafficking through prevacuolar compartments. GTPase activating proteins (GAPs) interact with GTP-bound Rab and accelerate the hydrolysis of GTP to GDP. Guanine nucleotide exchange factors (GEFs) interact with GDP-bound Rabs to promote the formation of the GTP-bound state. Rabs are further regulated by guanine nucleotide dissociation inhibitors (GDIs), which facilitate Rab recycling by masking C-terminal lipid binding and promoting cytosolic localization. Most Rab GTPases contain a lipid modification site at the C-terminus, with sequence motifs CC, CXC, or CCX. Lipid binding is essential for membrane attachment, a key feature of most Rab proteins. Due to the presence of truncated sequences in this CD, the lipid modification site is not available for annotation.
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基因ID
- 5868
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途径
- Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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