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RND3 抗体 (AA 51-150)

This anti-RND3 antibody is a 兔 多克隆 antibody detecting RND3 in ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人 和 大鼠.
产品编号 ABIN762356
发货至: 中国

Quick Overview for RND3 抗体 (AA 51-150) (ABIN762356)

抗原

See all RND3 抗体
RND3 (rho Family GTPase 3 (RND3))

适用

  • 31
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  • 1
  • 1
人, 大鼠

宿主

  • 16
  • 15

克隆类型

  • 17
  • 14
多克隆

标记

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  • 1
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This RND3 antibody is un-conjugated

应用范围

  • 17
  • 14
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  • 5
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  • 1
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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150

    交叉反应

    人, 大鼠

    预测反应

    Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human RND3

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    RND3 (rho Family GTPase 3 (RND3))

    别名

    Rnd3

    背景

    Synonyms: ARHE, memB, Rho family GTPase 3, Rho8, RhoE, RND3_HUMAN.

    Background: The Rho family of proteins mediates cytoskeleton organization and cell motility responses. This family contains twenty different members divided into five groups, the Rho-like, Rac-like, Cdc42-like, Rnd and RhoBTB subfamilies. Rho proteins have GTPase activity and bind GTP in their active form and GDP in their inactive form. In their active form they interact with downstream proteins. However, the Rnd subfamily of proteins containing the Rnd1, Rnd2 and RhoE(Rnd3), binds GTP but not GDP and has no GTPase activity. While Rho proteins are required for stress fibre formation in cultured fibroblasts, epithelial and endothelial cells, overexpression of Rnd3 or Rnd1 in the same cells may cause an opposite effect (i.e. decrease in stress fibre). Thus, the Rnd3 protein may act as an antagonist for the Rho proteins either by directly binding to Rho or to other downstream proteins.

    基因ID

    390
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