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Vitamin D Receptor 抗体 (AA 150-250)

The 小鼠 单克隆 anti-Vitamin D Receptor antibody (Clone AB2465) (ABIN8125720) specifically detects Vitamin D Receptor in WB, ELISA 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN8125720
发货至: 中国
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Quick Overview for Vitamin D Receptor 抗体 (AA 150-250) (ABIN8125720)

抗原

See all Vitamin D Receptor (VDR) 抗体
Vitamin D Receptor (VDR)

适用

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人

宿主

  • 148
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小鼠

克隆类型

  • 129
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单克隆

标记

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This Vitamin D Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)

克隆位点

AB2465
  • 抗原表位

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    AA 150-250

    原理

    Vitamin D Receptor mouse mAb

    特异性

    This antibody detects endogenous levels of Vitamin D Receptor protein.

    纯化方法

    The antibody was purified by protein G affinity chromatography.

    免疫原

    A synthetic peptide corresponding to the amino acid region 150 - 250 of the human Vitamin D Receptor protein.

    亚型

    IgG
  • 应用备注

    WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    Vitamin D Receptor (VDR)

    别名

    Vitamin D Receptor

    物质类

    Chemical

    背景

    Synonyms: Vitamin D3 receptor, VDR, 1, 25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1, NR1I1

    Background: vitamin D (1, 25-dihydroxyvitamin D3) receptor (VDR) Homo sapiens This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011],

    Gene Name: VDR

    Protein Name: Vitamin D Receptor

    基因ID

    7421

    UniProt

    P11473

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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