UCP1 抗体
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北京 101111
Quick Overview for UCP1 抗体 (ABIN8125608)
抗原
See all UCP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- UCP1 Rabbit mAb
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特异性
- This antibody detects endogenous levels of UCP1 protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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应用备注
- WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))
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别名
- UCP1
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背景
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Synonyms: Mitochondrial brown fat uncoupling protein 1 (UCP 1) (Solute carrier family 25 member 7) (Thermogenin)
Background: Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP) . UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH-are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. [provided by RefSeq, Jul 2008],
Gene Name: UCP1 SLC25A7 UCP
Protein Name: UCP1
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基因ID
- 7350
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UniProt
- P25874
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途径
- Proton Transport, Brown Fat Cell Differentiation
抗原
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