UCP1 抗体
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北京 101111
Quick Overview for UCP1 抗体 (ABIN8125607)
抗原
See all UCP1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- UCP1 Antibody
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特异性
- UCP1 Polyclonal Antibody detects endogenous levels of protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human protein
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亚型
- IgG
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应用备注
- WB 1:500-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))
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别名
- UCP1
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背景
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Background: Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. [provided by RefSeq, Jul 2008],
Gene Name: UCP1 SLC25A7 UCP
Protein Name: Mitochondrial brown fat uncoupling protein 1 (UCP 1) (Solute carrier family 25 member 7) (Thermogenin)
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基因ID
- 7350
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UniProt
- P25874
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途径
- Proton Transport, Brown Fat Cell Differentiation
抗原
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