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GALE 抗体 (AA 104-154)

This 兔 多克隆 antibody specifically detects GALE in WB. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN8125592
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GALE 抗体 (AA 104-154) (ABIN8125592)

抗原

See all GALE 抗体
GALE (UDP-Galactose-4-Epimerase (GALE))

适用

  • 64
  • 18
  • 16
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 58
  • 6
兔

克隆类型

  • 60
  • 4
多克隆

标记

  • 25
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GALE antibody is un-conjugated

应用范围

  • 45
  • 16
  • 13
  • 13
  • 11
  • 9
  • 6
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 12
    • 9
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 104-154

    原理

    GALE Antibody

    特异性

    This antibody detects endogenous levels of GALE at Human/Mouse/Rat

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human GALE AA range: 104-154

    亚型

    IgG
  • 应用备注

    WB 1:500-2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    GALE (UDP-Galactose-4-Epimerase (GALE))

    别名

    GALE

    背景

    Background: This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Jul 2008],

    Gene Name: GALE

    Protein Name: GALE

    基因ID

    2582

    UniProt

    Q14376

    途径

    Response to Water Deprivation, Cellular Glucan Metabolic Process
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