TNK2 抗体 (pTyr857, pTyr858)
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北京 101111
Quick Overview for TNK2 抗体 (pTyr857, pTyr858) (ABIN8125507)
抗原
See all TNK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr857, pTyr858
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原理
- Ack1 (Phospho Tyr857+Tyr858) Antibody
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特异性
- This antibody detects endogenous levels of Ack1 (Phospho-Tyr857+Tyr858) at Human, Mouse,Rat
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human Ack1 (Phospho-Tyr857+Tyr858)
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亚型
- IgG
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))
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别名
- Ack1
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背景
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Synonyms: Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)
Background: This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008],
Gene Name: TNK2 ACK1
Protein Name: Ack1 (Phospho-Tyr857+Tyr858)
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基因ID
- 10188
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UniProt
- Q07912
抗原
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