TNK1 抗体 (pTyr277)
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北京 101111
Quick Overview for TNK1 抗体 (pTyr277) (ABIN8125506)
抗原
See all TNK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr277
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原理
- TNK1 (Phospho Tyr277) Antibody
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特异性
- This antibody detects endogenous levels of Human TNK1 (phospho-Tyr277)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized phosho peptide around human TNK1 (Tyr277)
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亚型
- IgG
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应用备注
- WB 1:1000-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))
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别名
- TNK1
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背景
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Synonyms: Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)
Background: The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
Gene Name: TNK1
Protein Name: TNK1 (Tyr277)
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基因ID
- 8711
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UniProt
- Q13470
抗原
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