Tryptophan Hydroxylase 2 抗体 (pSer19)
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Quick Overview for Tryptophan Hydroxylase 2 抗体 (pSer19) (ABIN8125415)
抗原
See all Tryptophan Hydroxylase 2 (TPH2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer19
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原理
- TPH2 (phospho Ser19) Antibody
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特异性
- Phospho-TPH2 (S19) Polyclonal Antibody detects endogenous levels of TPH2 protein only when phosphorylated at S19.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized phospho-peptide around the phosphorylation site of human TPH2 (phospho Ser19)
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Tryptophan Hydroxylase 2 (TPH2)
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别名
- TPH2
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背景
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Synonyms: TPH2, NTPH, Tryptophan 5-hydroxylase 2, Neuronal tryptophan hydroxylase, Tryptophan 5-monooxygenase 2
Background: This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Feb 2016],
Gene Name: TPH2
Protein Name: Tryptophan 5-hydroxylase 2
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基因ID
- 121278
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UniProt
- Q8IWU9
抗原
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