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STING/TMEM173 抗体

This 兔 单克隆 antibody specifically detects STING/TMEM173 in WB, IHC, ELISA, IF 和 IP. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8125358
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for STING/TMEM173 抗体 (ABIN8125358)

抗原

See all STING/TMEM173 (TMEM173) 抗体
STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

适用

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人, 小鼠, 大鼠

宿主

  • 125
  • 9
兔

克隆类型

  • 85
  • 49
单克隆

标记

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This STING/TMEM173 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

AB1716
  • 原理

    TMEM173 Rabbit mAb

    特异性

    This antibody detects endogenous levels of TMEM173 protein.

    纯化方法

    The antibody was purified by protein A affinity chromatography.

    免疫原

    Recombinant protein (or fragment).

    亚型

    IgG
  • 应用备注

    WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

    别名

    TMEM173

    背景

    Synonyms: TMEM173, ERIS, MITA, STING, Transmembrane protein 173, Endoplasmic reticulum interferon stimulator, ERIS, Mediator of IRF3 activation, hMITA, Stimulator of interferon genes protein, hSTING

    Background: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014],

    Gene Name: TMEM173 ERIS MITA STING

    Protein Name: TMEM173

    基因ID

    340061

    UniProt

    Q86WV6

    途径

    Activation of Innate immune Response
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