STING/TMEM173 抗体
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北京 101111
Quick Overview for STING/TMEM173 抗体 (ABIN8125358)
抗原
See all STING/TMEM173 (TMEM173) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- TMEM173 Rabbit mAb
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特异性
- This antibody detects endogenous levels of TMEM173 protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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应用备注
- WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
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别名
- TMEM173
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背景
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Synonyms: TMEM173, ERIS, MITA, STING, Transmembrane protein 173, Endoplasmic reticulum interferon stimulator, ERIS, Mediator of IRF3 activation, hMITA, Stimulator of interferon genes protein, hSTING
Background: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014],
Gene Name: TMEM173 ERIS MITA STING
Protein Name: TMEM173
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基因ID
- 340061
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UniProt
- Q86WV6
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途径
- Activation of Innate immune Response
抗原
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