TMPRSS15 抗体 (Cleaved-Ile785, Light Chain)
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北京 101111
Quick Overview for TMPRSS15 抗体 (Cleaved-Ile785, Light Chain) (ABIN8125349)
抗原
See all TMPRSS15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Cleaved-Ile785, Light Chain
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原理
- ENTK (light chain, Cleaved-Ile785) Antibody
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特异性
- This antibody detects endogenous levels of Human ENTK (light chain, Cleaved-Ile785, protein was cleaved amino acid sequence between 785-786 )
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human ENTK (light chain, Cleaved-Ile785)
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亚型
- IgG
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应用备注
- WB 1:1000-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TMPRSS15 (Transmembrane Protease, serine 15 (TMPRSS15))
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别名
- ENTK
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背景
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Synonyms: Enteropeptidase (EC 3.4.21.9, Enterokinase, Serine protease 7, Transmembrane protease serine 15) [Cleaved into: Enteropeptidase non-catalytic heavy chain, Enteropeptidase catalytic light chain]
Background: catalytic activity:Activation of trypsinogen by selective cleavage of 6-Lys-|-Ile-7 bond.,disease:Defects in PRSS7 are a cause of enterokinase deficiency [MIM:226200], a life-threatening intestinal malabsorption disorder characterized by diarrhea and failure to thrive.,function:Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.,PTM:The chains are derived from a single precursor that is cleaved by a trypsin-like protease.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 MAM domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 1 SEA domain.,similarity:Contains 1 SRCR domain.,similarity:Contains 2 CUB domains.,similarity:Contains 2 LDL-receptor class A domains.,subunit:Heterodimer of a catalytic (light) chain and a multidomain (heavy) chain linked by a disulfide bond.,tissue specificity:Intestinal brush border.,
Gene Name: TMPRSS15 ENTK PRSS7
Protein Name: ENTK (light chain, Cleaved-Ile785)
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基因ID
- 5651
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UniProt
- P98073
抗原
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