TTF1 抗体 (pSer327)
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Quick Overview for TTF1 抗体 (pSer327) (ABIN8125284)
抗原
See all TTF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer327
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原理
- TTF-1 (Phospho Ser327) Antibody
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特异性
- This antibody detects endogenous levels of Human TTF-1 (phospho-Ser327)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized phosho peptide around human TTF-1 (Ser327)
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亚型
- IgG
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应用备注
- WB 1:1000-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))
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别名
- TTF-1
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背景
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Synonyms: Homeobox protein Nkx-2.1 (Homeobox protein NK-2 homolog A) (Thyroid nuclear factor 1) (Thyroid transcription factor 1) (TTF-1)
Background: This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014],
Gene Name: NKX2-1 NKX2A TITF1 TTF1
Protein Name: TTF-1 (Ser327)
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基因ID
- 7080
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UniProt
- P43699
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途径
- Thyroid Hormone Synthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
抗原
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