TTF1 抗体 (AA 50-150)
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北京 101111
Quick Overview for TTF1 抗体 (AA 50-150) (ABIN8125283)
抗原
See all TTF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 50-150
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原理
- TTF1 mouse mAb
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特异性
- The antibody can specifically recognize human TTF1 protein.
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纯化方法
- The antibody was purified by protein G affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 50 - 150 of the human TTF1 protein.
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亚型
- IgG
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应用备注
- IHC, 1:50-1:200 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))
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别名
- TTF1
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背景
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Synonyms: AV026640, BCH, Benign chorea, BHC, Homeobox protein NK 2 homolog A, Homeobox protein NK-2 homolog A, Homeobox protein Nkx 2. 1, Homeobox protein Nkx-2. 1, Homeobox protein Nkx2. 1, NK 2, NK 2 homolog A, NK2, NK2 homeobox 1, NK2, drosophila, homolog of, A, NK2. 1, Mouse, homolog of, Nkx 2 1, NKX 2. 1, NKX 2A, NKX2 1, Nkx2-1, NKX2. 1, NKX21_HUMAN, NKX2A, T EBP, T/EBP, TEBP, Thyroid nuclear factor 1, Thyroid nuclear factor, Thyroid specific enhancer binding protein, Thyroid transcription factor 1, Tin man, Tinman, TITF 1, TITF1, TTF 1, TTF-1, TTF1
Background: Thyroid transcription factor 1 (TTF-1) is a nuclear protein with a molecular weight of 38-40 kDa. It is the basic material for thyroid differentiation and the regulation of thyroglobulin secretion. It can promote the transport of thyroid peroxidase and iodine / sodium. TTF-1 is mainly distributed in type II alveolar epithelium, respiratory epithelium and Clara cells of thyroid and lung in adult tissues, but it is not expressed in type I alveolar epithelium. It is mainly used for the diagnosis of small cell lung cancer, the differential diagnosis of primary lung adenocarcinoma from metastatic adenocarcinoma, and the differential diagnosis of lung cancer from malignant mesothelioma and paraganglioma of pleura.
Gene Name: NKX2-1
Protein Name: TTF1
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基因ID
- 7080
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UniProt
- P43699
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途径
- Thyroid Hormone Synthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
抗原
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