Thyroperoxidase 抗体 (AA 600-700)
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Quick Overview for Thyroperoxidase 抗体 (AA 600-700) (ABIN8125211)
抗原
See all Thyroperoxidase (TPO) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 600-700
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原理
- Thyroid Peroxidase (TPO) mouse mAb
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特异性
- This antibody detects endogenous levels of TPO protein.
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纯化方法
- The antibody was purified by protein G affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 600 - 700 of the human Thyroid Peroxidase protein.
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亚型
- IgG
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应用备注
- IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
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别名
- Thyroid Peroxidase
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背景
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Synonyms: Thyroid peroxidase,TPO,
Background: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]
Gene Name: TPO
Protein Name: Thyroid Peroxidase (TPO)
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基因ID
- 3662
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UniProt
- P07202
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途径
- Thyroid Hormone Synthesis
抗原
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