Thymopoietin 抗体
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北京 101111
Quick Overview for Thymopoietin 抗体 (ABIN8125200)
抗原
See all Thymopoietin (TMPO) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- LAP2B Antibody
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特异性
- LAP2B Polyclonal Antibody detects endogenous levels of protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human protein
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亚型
- IgG
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anti-Thymopoietin (TMPO) (AA 1-410) antibody
TMPO 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thymopoietin (TMPO) antibodyTMPO 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Thymopoietin (TMPO) (AA 1-243) antibodyTMPO 适用: 人 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Thymopoietin (TMPO) (Internal Region) antibodyTMPO 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thymopoietin (TMPO) (AA 200-250) antibodyTMPO 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Thymopoietin (TMPO) (AA 1-454) antibodyTMPO 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Thymopoietin (TMPO) antibodyTMPO 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thymopoietin (TMPO) (AA 650-750) antibodyTMPO 适用: 人 WB, IF, ICC, IP 宿主: 小鼠 Monoclonal 3A3 unconjugated
anti-Thymopoietin (TMPO) (AA 243-269) antibodyTMPO 适用: 人 WB 宿主: 兔 Polyclonal RB39917 unconjugated
anti-Thymopoietin (TMPO) (N-Term) antibodyTMPO 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, Pig, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Thymopoietin (TMPO)
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别名
- LAP2B
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背景
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Background: alternative products:Additional isoforms seem to exist,domain:Has two structurally independent, non-interacting domains: LEM-like (also called LAP2-N or LEM-D) and LEM (also called LAP2-C or LEM-B). LEM-like binds DNA while LEM interacts with BANF1.,function:May be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. Play an important role, together with LMNA, in the nuclear anchorage of RB1.,function:May help direct the assembly of the nuclear lamina and thereby help maintain the structural organization of the nuclear envelope. Possible receptor for attachment of lamin filaments to the inner nuclear membrane. May be involved in the control of initiation of DNA replication through its interaction with NAKAP95.,function:TP and TP5 may play a role in T-cell development and function. TP5 is an immunomodulating pentapeptide.,pharmaceutical:TP5 is available under the names Timunox (Cilag), Sintomodulina (Italofarmaco) and Mepentil (Recordati). Used in primary and secondary immune deficiencies, autoimmunity, infections and cancer.,PTM:Mitosis-specific phosphorylation specifically abolishes its binding to lamin B and chromosomes.,PTM:Phosphorylated in a mitose-specific manner.,similarity:Belongs to the LEM family.,similarity:Contains 1 LEM domain.,similarity:Contains 1 LEM-like domain.,subcellular location:Expressed diffusely throughout the nucleus.,subcellular location:Tightly associated with the nuclear lamina.,subunit:Interacts with LMNA, BANF1 and RB1 and with chromosomes. Associates directly or indirectly with lamins at specific cell-cycle stages.,subunit:Interacts with LMNB1, LMNB2, BANF1, NAKAP95, GMCL and chromosomes.,tissue specificity:Expressed in many tissues. Most abundant in adult thymus and fetal liver.,
Gene Name: TMPO LAP2
Protein Name: Lamina-associated polypeptide 2, isoforms beta/gamma (Thymopoietin, isoforms beta/gamma) (TP beta/gamma) (Thymopoietin-related peptide isoforms beta/gamma) (TPRP isoforms beta/gamma) [Cleaved into: Thymopoietin (TP) (Splenin)Thymopentin (TP5)]
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基因ID
- 7112
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UniProt
- P42167
抗原
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