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TGIF1 抗体

The 兔 多克隆 anti-TGIF1 antibody (ABIN8125162) specifically detects TGIF1 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8125162
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TGIF1 抗体 (ABIN8125162)

抗原

See all TGIF1 抗体
TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

适用

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  • 1
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  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 43
  • 6
兔

克隆类型

  • 43
  • 6
多克隆

标记

  • 30
  • 4
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  • 3
  • 2
  • 2
  • 1
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This TGIF1 antibody is un-conjugated

应用范围

  • 42
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  • 6
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Western Blotting (WB), ELISA
  • 原理

    TGIF Antibody

    特异性

    TGIF Polyclonal Antibody detects endogenous levels of TGIF protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from the C-terminal region of human TGIF.

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

    别名

    TGIF

    背景

    Synonyms: TGIF1, TGIF, Homeobox protein TGIF1, 5'-TG-3'-interacting factor 1

    Background: The protein encoded byThis gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described. [provide

    Gene Name: TGIF1

    Protein Name: Homeobox protein TGIF1

    基因ID

    7050

    UniProt

    Q15583

    途径

    Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation
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