TBC1D4 抗体
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北京 101111
Quick Overview for TBC1D4 抗体 (ABIN8125129)
抗原
See all TBC1D4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- TBC1D4 Rabbit mAb
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特异性
- This antibody detects endogenous levels of TBC1D4 protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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anti-TBC1 Domain Family, Member 4 (TBC1D4) (AA 1118-1298) antibody
TBC1D4 适用: 人 WB, ELISA, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 4 (TBC1D4) (AA 574-712) antibodyTBC1D4 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 8A11A2 unconjugated
anti-TBC1 Domain Family, Member 4 (TBC1D4) (AA 172-201), (N-Term) antibodyTBC1D4 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21034 unconjugated
anti-TBC1 Domain Family, Member 4 (TBC1D4) (AA 1-94) antibodyTBC1D4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 4 (TBC1D4) (Internal Region) antibodyVerified TBC1D4 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 4 (TBC1D4) (pSer588) antibodyTBC1D4 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 4 (TBC1D4) (pSer318) antibodyTBC1D4 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 4 (TBC1D4) antibodyTBC1D4 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB890 unconjugated Recombinant Antibody
anti-TBC1 Domain Family, Member 4 (TBC1D4) antibodyTBC1D4 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 4 (TBC1D4) (AA 1155-1204) antibodyTBC1D4 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB, 1:2000-1:10000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- TBC1D4 (TBC1 Domain Family, Member 4 (TBC1D4))
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别名
- TBC1D4
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背景
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Synonyms: TBC1D4, AS160, KIAA0603, TBC1 domain family member 4, Akt substrate of 160 kDa, AS160
Background: This gene is a member of the Tre-2/BUB2/CDC16 domain family. The protein encoded by this gene is a Rab-GTPase-activating protein, and contains two phopshotyrosine-binding domains (PTB1 and PTB2) , a calmodulin-binding domain (CBD) , a Rab-GTPase domain, and multiple AKT phosphomotifs. This protein is thought to play an important role in glucose homeostasis by regulating the insulin-dependent trafficking of the glucose transporter 4 (GLUT4) , important for removing glucose from the bloodstream into skeletal muscle and fat tissues. Reduced expression of this gene results in an increase in GLUT4 levels at the plasma membrane, suggesting that this protein is important in intracellular retention of GLUT4 under basal conditions. When exposed to insulin, this protein is phosphorylated, dissociates from GLUT4 vesicles, resulting in increased GLUT4 at the cell surface, and enhanced glucose transport. Ph
Gene Name: TBC1D4
Protein Name: TBC1D4
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基因ID
- 9882
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UniProt
- O60343
抗原
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