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TAPBP 抗体

This 兔 多克隆 antibody specifically detects TAPBP in WB 和 ELISA. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN8125112
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TAPBP 抗体 (ABIN8125112)

抗原

See all TAPBP 抗体
TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

适用

  • 24
  • 8
  • 6
  • 5
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 22
  • 2
兔

克隆类型

  • 22
  • 2
多克隆

标记

  • 19
  • 1
  • 1
  • 1
  • 1
  • 1
This TAPBP antibody is un-conjugated

应用范围

  • 22
  • 9
  • 5
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 原理

    TPSN Antibody

    特异性

    TPSN Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human protein

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

    别名

    TPSN

    背景

    Background: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

    Gene Name: TAPBP NGS17 TAPA

    Protein Name: Tapasin (TPN) (TPSN) (NGS-17) (TAP-associated protein) (TAP-binding protein)

    基因ID

    6892

    UniProt

    O15533
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