TCL1A 抗体 (AA 50-114)
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北京 101111
Quick Overview for TCL1A 抗体 (AA 50-114) (ABIN8125093)
抗原
See all TCL1A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 50-114
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原理
- TCL1 mouse mAb
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特异性
- The antibody can specifically recognize human TCL1 protein.
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纯化方法
- The antibody was purified by protein G affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 50 - 114 of the human TCL1 protein.
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亚型
- IgG
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应用备注
- IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
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别名
- TCL1
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背景
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Synonyms: Anti TCL1A, Lymphoma/leukemia, T-cell, Oncogene TCL-1, Oncogene TCL1, P14 TCL1, P14 TCL1 protein, Protein p14 TCL1, T cell leukemia 1, T cell lymphoma 1, T cell lymphoma 1A, T-cell leukemia/lymphoma 1A, T-cell leukemia/lymphoma protein 1A, TCL 1 protein, TCL1, TCL1 oncogene, TCL1 PEN, Tcl1a, TCL1A, TCL1A_HUMAN
Background: TCL1 belongs to the proto oncogene family. It promotes the nuclear translocation of AKT1 by activating the phosphorylation of AKT1, AKT2 and Akt3, so as to promote cell proliferation and survival and stabilize mitochondrial membrane potential. The encoded protein is involved in embryonic development, T cell carcinogenesis, pre lymphocyte carcinogenesis and B cell carcinogenesis.
Gene Name: TCL1A
Protein Name: TCL1
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基因ID
- 8115
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UniProt
- P56279
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途径
- Stem Cell Maintenance
抗原
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