Synovial Sarcoma, X Breakpoint 2B (SSX2B) (AA 139-188) 抗体
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Quick Overview for Synovial Sarcoma, X Breakpoint 2B (SSX2B) (AA 139-188) 抗体 (ABIN8125065)
抗原
See all Synovial Sarcoma, X Breakpoint 2B (SSX2B) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 139-188
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原理
- SSX Antibody
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特异性
- SSX Polyclonal Antibody detects endogenous levels of SSX protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the C-terminal region of human SSX1/2/3/4/5/6/7/8/9. AA range:139-188
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亚型
- IgG
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anti-Synovial Sarcoma, X Breakpoint 2B (SSX2B) (C-Term) antibody
SSX2B 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Synovial Sarcoma, X Breakpoint 2B (SSX2B) (N-Term) antibodySSX2B 适用: 人, 小鼠, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Synovial Sarcoma, X Breakpoint 2B (SSX2B)
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别名
- SSX
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背景
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Synonyms: SSX1, Protein SSX1, Cancer/testis antigen 5.1, CT5.1, Synovial sarcoma, X breakpoint 1, SSX2, SSX2A, SSX2B, Protein SSX2, Cancer/testis antigen 5.2, CT5.2, Synovial sarcoma, X breakpoint 2, Tumor antigen HOM-MEL-40, SSX3, Protein SSX3, Cancer/testis antigen 5.3, CT5.3, SSX4, SSX4A, SSX4B, Protein SSX4, Cancer/testis antigen 5.4, CT5.4, SSX5, Protein SSX5, SSX6, Putative protein SSX6, SSX7, Protein SSX7, SSX8, Protein SSX8, SSX9, Protein SSX9
Background: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX2 and SSX4 family members, have been involved in t(X,18)(p11.2,q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Jul 2013],
Gene Name: SSX1/SSX2/SSX3/SSX4/SSX5/SSX6/SSX7/SSX8/SSX9
Protein Name: Protein SSX1/Protein SSX2/Protein SSX3/Protein SSX4/Protein SSX5/Protein SSX6/Protein SSX7/Protein SSX8/Protein SSX9
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基因ID
- 6756
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UniProt
- Q16384
抗原
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