SOCS3 抗体 (AA 20-70)
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北京 101111
Quick Overview for SOCS3 抗体 (AA 20-70) (ABIN8125023)
抗原
See all SOCS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-70
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原理
- SOCS-3 Antibody
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特异性
- The antibody detects endogenous SOCS-3
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthetic peptide from human protein at AA range: 20-70
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000.IHC:1:50-300.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
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别名
- SOCS-3
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背景
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Synonyms: Suppressor of cytokine signaling 3 (SOCS-3, Cytokine-inducible SH2 protein 3, CIS-3, STAT-induced STAT inhibitor 3, SSI-3)
Background: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma.The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008],
Gene Name: SOCS3 CIS3 SSI3
Protein Name: Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (STAT-induced STAT inhibitor 3) (SSI-3)
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基因ID
- 9021
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UniProt
- O14543
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途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus, Hepatitis C
抗原
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