STIM1 抗体
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Quick Overview for STIM1 抗体 (ABIN8124991)
抗原
See all STIM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Stromal Interaction Molecule 1 Rabbit mAb
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特异性
- This antibody detects endogenous levels of Stromal Interaction Molecule 1 protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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anti-Stromal Interaction Molecule 1 (STIM1) (AA 24-685) antibody
STIM1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5A2 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 1-211) antibodySTIM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (N-Term) antibodySTIM1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (C-Term) antibodySTIM1 适用: 人, 小鼠, 大鼠 WB, IP, ICC, IHC (p) 宿主: 小鼠 Monoclonal CDN3H4 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) antibodyKD Validated STIM1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2415 unconjugated Recombinant Antibody
anti-Stromal Interaction Molecule 1 (STIM1) (AA 56-69), (Extracellular), (Lumenal Loop), (N-Term) antibodyKO Validated STIM1 适用: 人 WB, IHC, IF, IP, FACS, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 509-538), (C-Term) antibodySTIM1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB19222 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 24-686) antibodySTIM1 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5A2 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 56-69), (Extracellular), (Lumenal Loop), (N-Term) antibody (Atto 550)STIM1 适用: 人 IHC, IF, FACS, IC, LCI 宿主: 兔 Polyclonal Atto 550
anti-Stromal Interaction Molecule 1 (STIM1) (C-Term) antibodySTIM1 适用: 人, 小鼠, 大鼠 WB, IHC, IP, ICC, IHC (p), InhibAb 宿主: 小鼠 Monoclonal CDN3H4 unconjugated
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应用备注
- WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- STIM1 (Stromal Interaction Molecule 1 (STIM1))
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别名
- Stromal Interaction Molecule 1
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背景
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Synonyms: Stromal interaction molecule 1
Background: This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs) . It is one of several genes located in the imprinted gene domain of 11p15. 5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1) , with the 3' end of this gene situated 1. 6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
Gene Name: STIM1
Protein Name: Stromal Interaction Molecule 1
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基因ID
- 6786
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UniProt
- Q13586
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途径
- TCR Signaling, BCR Signaling
抗原
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