STIP1 抗体 (AA 250-300)
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北京 101111
Quick Overview for STIP1 抗体 (AA 250-300) (ABIN8124986)
抗原
See all STIP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 250-300
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原理
- STIP1/HOP Antibody
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特异性
- This antibody detects endogenous levels of STIP1/HOP at Human, Mouse,Rat
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human STIP1/HOP AA range: 250-300
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亚型
- IgG
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应用备注
- IHC1:50-200 ,WB 1:1000-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))
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别名
- STIP1/HOP
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背景
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Synonyms: Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)
Background: STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A, MIM 140550) and HSP90 (see HSP90AA1, MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009],
Gene Name: STIP1
Protein Name: STIP1/HOP
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基因ID
- 10963
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UniProt
- P31948
抗原
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