STARD4 抗体
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北京 101111
Quick Overview for STARD4 抗体 (ABIN8124947)
抗原
See all STARD4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- STARD4 Rabbit mAb
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特异性
- This antibody detects endogenous levels of STARD4 protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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应用备注
- WB, 1:1000-1:5000 | IF, 1:100-1:300 |
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- STARD4 (StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4))
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别名
- STARD4
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背景
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Synonyms: STARD4, StAR-related lipid transfer protein 4 , START domain-containing protein 4, StARD4,
Background: Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e. g. , SREBP1, MIM 184756) and by liver X receptors (e. g. , LXRA, MIM 602423) . Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR, MIM 600617) . STAR is homologous to a family of proteins containing a 200-to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al. , 2002 [PubMed 12011452]) . [supplied by OMIM, Mar 2008]
Gene Name: STARD4
Protein Name: STARD4
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基因ID
- 134429
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UniProt
- Q96DR4
抗原
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