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SPAG8 抗体

The 兔 多克隆 anti-SPAG8 antibody is suitable to detect SPAG8 in samples from 人, 小鼠 和 大鼠. It has been validated for ELISA 和 WB.
产品编号 ABIN8124882
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SPAG8 抗体 (ABIN8124882)

抗原

See all SPAG8 抗体
SPAG8 (Sperm Associated Antigen 8 (SPAG8))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

  • 50
  • 2
多克隆

标记

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This SPAG8 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB)
  • 原理

    SPAG8 Antibody

    特异性

    SPAG8 Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human protein

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    SPAG8 (Sperm Associated Antigen 8 (SPAG8))

    别名

    SPAG8

    背景

    Background: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens.The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. This protein interacts with ACT (activator of CREM in testis) and may play a role in CREM (cAMP response element modulator)-ACT-mediated gene transcription during spermatogenesis. This protein may also play a role in spermatogenesis by regulating microtubule formation and cell division. Al

    Gene Name: SPAG8

    Protein Name: Sperm-associated antigen 8 (HSD-1) (Sperm membrane protein 1) (SMP-1) (Sperm membrane protein BS-84)

    基因ID

    26206

    UniProt

    Q99932
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