SLC22A6 抗体
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北京 101111
Quick Overview for SLC22A6 抗体 (ABIN8124803)
抗原
See all SLC22A6 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- OAT1 Antibody
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特异性
- This antibody detects endogenous levels of OAT1.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human OAT1 Polyclonal
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亚型
- IgG
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anti-Solute Carrier Family 22 Member 6 (SLC22A6) (C-Term) antibody
SLC22A6 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 22 Member 6 (SLC22A6) (AA 513-541), (C-Term) antibodySLC22A6 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23819 unconjugated
anti-Solute Carrier Family 22 Member 6 (SLC22A6) (Internal Region) antibodySLC22A6 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 22 Member 6 (SLC22A6) (C-Term) antibodySLC22A6 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 22 Member 6 (SLC22A6) antibodySLC22A6 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 22 Member 6 (SLC22A6) (C-Term) antibodySLC22A6 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 马, 兔, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 22 Member 6 (SLC22A6) (AA 451-550) antibodySLC22A6 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1F2 unconjugated
anti-Solute Carrier Family 22 Member 6 (SLC22A6) (AA 513-541) antibodySLC22A6 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 22 Member 6 (SLC22A6) (N-Term) antibodySLC22A6 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 马, 兔, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 22 Member 6 (SLC22A6) (N-Term) antibodySLC22A6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000, IF ICC 1:100-500,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))
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别名
- OAT1
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背景
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Background: domain:Multiple cysteine residues are necessary for proper targeting to the plasma membrane.,function:Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) (By similarity). Mediates the sodium-independent uptake of p-aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV), 3'-azido-3-'deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), hippurate (HA), indoleacetate (IA), indoxyl sulfate (IS) and 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF), cidofovir, adefovir, 9-(2-phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP) and edaravone sulfate. PAH uptake is inhibited by p-chloromercuribenzenesulphonate (PCMBS), diethyl pyrocarbonate (DEPC), sulindac, diclofenac, carprofen, glutarate and okadaic acid (By similarity). PAH uptake is inhibited by benzothiazolylcysteine (BTC), S-chlorotrifluoroethylcysteine (CTFC), cysteine S-conjugates S-dichlorovinylcysteine (DCVC), furosemide, steviol, phorbol 12-myristate 13-acetate (PMA), calcium ionophore A23187, benzylpenicillin, furosemide, indomethacin, bumetamide, losartan, probenecid, phenol red, urate, and alpha-ketoglutarate.,PTM:Glycosylated. Glycosylation at Asn-113 may occur at a secondary level. Glycosylation is necesssary for proper targeting of the transporter to the plasma membrane.,similarity:Belongs to the major facilitator superfamily. Organic cation transporter family.,tissue specificity:Strongly expressed in kidney and to a lower extent in liver, skeletal muscle, brain and placenta. Found at the basolateral membrane of the proximal tubule.,
Protein Name: OAT1
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UniProt
- O95742
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途径
- Dicarboxylic Acid Transport
抗原
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