Smad1/9 抗体 (AA 400-465)
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北京 101111
Quick Overview for Smad1/9 抗体 (AA 400-465) (ABIN8124750)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 400-465
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原理
- Smad1/9 mouse mAb
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特异性
- This antibody detects endogenous levels of Smad1/9 protein.
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纯化方法
- The antibody was purified by protein G affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 400 - 465 of the human Smad1/9 protein.
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亚型
- IgG
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应用备注
- WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- Smad1/9
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背景
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Synonyms: Mothers against decapentaplegic homolog 1, MAD homolog 1, Mothers against DPP homolog 1, JV4-1, Mad-related protein 1, SMAD family member 1 (SMAD 1, Smad1, hSMAD1) , Transforming growth factor-beta-signaling protein 1 (BSP-1) , SMAD1, BSP1, MADH1, MADR1, Mothers against decapentaplegic homolog 9, MAD homolog 9, Mothers against DPP homolog 9, Madh6, SMAD family member 9 (SMAD 9, Smad9) , SMAD9, MADH6, MADH9, SMAD8
Background: SMAD family member 1 (SMAD1) Homo sapiens The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs) , which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-med
Gene Name: SMAD1 SMAD9
Protein Name: Smad1/9
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基因ID
- 4086
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UniProt
- Q15797
抗原
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