SMAD7 抗体 (acLys70)
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北京 101111
Quick Overview for SMAD7 抗体 (acLys70) (ABIN8124749)
抗原
See all SMAD7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- acLys70
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原理
- Smad7 (Acetyl Lys70) Antibody
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特异性
- This antibody detects endogenous levels of Human,Mouse,Rat Smad7 (Acetyl Lys70)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human Smad7 (Acetyl Lys70)
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亚型
- IgG
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anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 1-100) antibody
SMAD7 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) antibodySMAD7 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G10 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) antibodySMAD7 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3E9 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 195-224) antibodySMAD7 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB18598 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) antibodySMAD7 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 4C11 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 302-400) antibodySMAD7 适用: 人 IF 宿主: 小鼠 Monoclonal 3A11 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 195-224) antibodySMAD7 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (N-Term) antibodySMAD7 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 36-247) antibodySMAD7 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 49-317) antibodySMAD7 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000,IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
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别名
- Smad7
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背景
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Synonyms: Mothers against decapentaplegic homolog 7 (MAD homolog 7, Mothers against DPP homolog 7, Mothers against decapentaplegic homolog 8, MAD homolog 8, Mothers against DPP homolog 8, SMAD family member 7, SMAD 7, Smad7, hSMAD7)
Background: The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010],
Gene Name: SMAD7 MADH7 MADH8
Protein Name: Smad7 (Acetyl Lys70)
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基因ID
- 4092
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UniProt
- O15105
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途径
- Interferon-gamma Pathway, Cell-Cell Junction Organization
抗原
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