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RAP1GAP 抗体 (AA 460-540)

The 兔 多克隆 anti-RAP1GAP antibody (ABIN8124232) specifically detects RAP1GAP in WB, IHC, ELISA 和 IF. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN8124232
发货至: 中国
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Quick Overview for RAP1GAP 抗体 (AA 460-540) (ABIN8124232)

抗原

See all RAP1GAP 抗体
RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

适用

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  • 1
人, 小鼠

宿主

  • 48
  • 11
兔

克隆类型

  • 33
  • 26
多克隆

标记

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This RAP1GAP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 460-540

    原理

    Rap1GAP Antibody

    特异性

    Rap1GAP Polyclonal Antibody detects endogenous levels of Rap1GAP protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from Rap1GAP . at AA range: 460-540

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

    别名

    Rap1GAP

    背景

    Synonyms: RAP1GAP, KIAA0474, RAP1GA1, Rap1 GTPase-activating protein 1, Rap1GAP, Rap1GAP1

    Background: RAP1 GTPase activating protein(RAP1GAP) Homo sapiens This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Aug 2011],

    Gene Name: RAP1GAP

    Protein Name: Rap1 GTPase-activating protein 1

    基因ID

    5909

    UniProt

    P47736
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