RAD17 抗体 (pSer635)
Our Local Distributor
北京 101111
Quick Overview for RAD17 抗体 (pSer635) (ABIN8124219)
抗原
See all RAD17 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer635
-
原理
- Rad17 (Phospho Ser635) Antibody
-
特异性
- This antibody detects endogenous levels of Human Rad17 (phospho-Ser635)
-
纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-
免疫原
- Synthesized phosho peptide around human Rad17 (Ser635)
-
亚型
- IgG
-
-
anti-RAD17 (RAD17) (pSer656) antibody
KD Validated RAD17 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB795 unconjugated Recombinant Antibody
anti-RAD17 (RAD17) (AA 1-584) antibodyRAD17 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (AA 1-267) antibodyRAD17 适用: 小鼠, 大鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (AA 391-670) antibodyRAD17 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (pSer645) antibodyRAD17 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (AA 1-110) antibodyRAD17 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G12 unconjugated
anti-RAD17 (RAD17) (AA 1-270) antibodyRAD17 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) antibodyKD Validated RAD17 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (AA 218-246) antibodyRAD17 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB20035 unconjugated
anti-RAD17 (RAD17) (C-Term) antibodyKO Validated, KD Validated RAD17 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- RAD17
-
别名
- Rad17
-
背景
-
Synonyms: Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog)
Background: The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, h
Gene Name: RAD17 R24L
Protein Name: Rad17 (Ser635)
-
基因ID
- 5884
-
UniProt
- O75943
抗原
-
