RAB5 抗体
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北京 101111
Quick Overview for RAB5 抗体 (ABIN8124212)
抗原
See all RAB5 (RAB5A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Rab 5A Rabbit mAb
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特异性
- This antibody detects endogenous levels of Rab 5A protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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应用备注
- WB, 1:1000-1:5000 | IHC, 1:1000-1:4000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))
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别名
- Rab 5A
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背景
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Synonyms: RAB5A, RAB5, Ras-related protein Rab-5A
Background: enzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP. , function:Required for the fusion of plasma membranes and early endosomes. , similarity:Belongs to the small GTPase superfamily. Rab family. , subcellular location:Enriched in stage I melanosomes. , subunit:Binds EEA1. Interacts with RIN1 and GAPVD1, which regulate its pathway, probably by acting as a GEF. Interacts with ALS2CL, UNC84B, ZFYVE20 and RUFY1. Interacts with SGSM1 and SGSM3. ,
Gene Name: >>Ras signaling pathway, >>Endocytosis, >>Phagosome, >>Vasopressin-regulated water reabsorption, >>Amyotrophic lateral sclerosis, >>Pathways of neurodegeneration-multiple diseases, >>Salmonella infection, >>Amoebiasis, >>Tuberculosis
Protein Name: Rab 5A
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基因ID
- 5868
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UniProt
- P20339
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途径
- Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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