Proteasome alpha3 (AA 190-270) 抗体
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Quick Overview for Proteasome alpha3 (AA 190-270) 抗体 (ABIN8124041)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 190-270
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原理
- Proteasome α3 Antibody
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特异性
- This antibody detects endogenous levels of Human,Mouse,Rat Proteasome α3
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human Proteasome alpha3 AA range: 190-270
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亚型
- IgG
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anti-Proteasome alpha3 (AA 206-255), (pSer250) antibody
适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000,IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Proteasome alpha3
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背景
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Synonyms: Proteasome subunit alpha type-3 (EC 3.4.25.1, Macropain subunit C8, Multicatalytic endopeptidase complex subunit C8, Proteasome component C8)
Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
Gene Name: PSMA3 HC8 PSC8
Protein Name: Proteasome α3
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基因ID
- 5684
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UniProt
- P25788
抗原
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