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PTGIS 抗体

The 兔 多克隆 anti-PTGIS antibody is suitable to detect PTGIS in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA 和 IHC.
产品编号 ABIN8124006
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PTGIS 抗体 (ABIN8124006)

抗原

See all PTGIS 抗体
PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))

适用

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人, 小鼠, 大鼠

宿主

  • 54
  • 8
  • 2
  • 1
兔

克隆类型

  • 60
  • 5
多克隆

标记

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This PTGIS antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 原理

    PGI2 synthase Antibody

    特异性

    PGI2 synthase Polyclonal Antibody detects endogenous levels of PGI2 synthase protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from the C-terminal region of human PGI2 synthase.

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))

    别名

    PGI2 synthase

    背景

    Synonyms: PTGIS, CYP8, CYP8A1, Prostacyclin synthase, Prostaglandin I2 synthase

    Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008],

    Gene Name: PTGIS

    Protein Name: Prostacyclin synthase

    基因ID

    5740

    UniProt

    Q16647
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