PTGIS 抗体
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北京 101111
Quick Overview for PTGIS 抗体 (ABIN8124006)
抗原
See all PTGIS 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PGI2 synthase Antibody
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特异性
- PGI2 synthase Polyclonal Antibody detects endogenous levels of PGI2 synthase protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the C-terminal region of human PGI2 synthase.
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))
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别名
- PGI2 synthase
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背景
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Synonyms: PTGIS, CYP8, CYP8A1, Prostacyclin synthase, Prostaglandin I2 synthase
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008],
Gene Name: PTGIS
Protein Name: Prostacyclin synthase
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基因ID
- 5740
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UniProt
- Q16647
抗原
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