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Prohibitin 2 抗体

The 兔 多克隆 anti-Prohibitin 2 antibody (ABIN8123962) specifically detects Prohibitin 2 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8123962
发货至: 中国
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Quick Overview for Prohibitin 2 抗体 (ABIN8123962)

抗原

See all Prohibitin 2 (PHB2) 抗体
Prohibitin 2 (PHB2)

适用

  • 118
  • 60
  • 54
  • 11
  • 8
  • 8
  • 7
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 104
  • 15
  • 1
兔

克隆类型

  • 90
  • 30
多克隆

标记

  • 61
  • 7
  • 6
  • 6
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Prohibitin 2 antibody is un-conjugated

应用范围

  • 107
  • 58
  • 39
  • 37
  • 35
  • 33
  • 18
  • 14
  • 14
  • 10
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 原理

    PHB2 Antibody

    特异性

    PHB2 Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human protein

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Prohibitin 2 (PHB2)

    别名

    PHB2

    背景

    Background: developmental stage:Levels of expression in fibroblasts decrease heterogeneously during cellular aging.,function:Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.,induction:Expression increases approximately 3-fold upon entry into G1 phase compared to other phases of the cell cycle. Also induced following inhibition of mitochondrial protein synthesis by thiamphenicol.,similarity:Belongs to the prohibitin family.,subcellular location:Also cytoplasmic and nuclear.,subunit:Interacts with PHB, ESR1, HDAC1 and HDAC5.,

    Gene Name: PHB2 BAP REA

    Protein Name: Prohibitin-2 (B-cell receptor-associated protein BAP37) (D-prohibitin) (Repressor of estrogen receptor activity)

    基因ID

    11331

    UniProt

    Q99623

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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